RA is a serious autoimmune disease that is much different from osteoarthritis, the type that usually occurs as we age.Rheumatoid arthritis can strike at any age, and if you don’t get diagnosed and treated, you could develop painful crippling and deformity.

A devastating disease that can severely damage your joints, RA also affects other organs and reduces your life expectancy. Newer treatments are very successful at reducing joint pain and damage, and remission is a real possibility. But early treatment is essential to avoid permanent joint damage and disability.

6 Signs and Symptoms of Rheumatoid Arthritis

Sometimes it can be difficult to tell whether your symptoms are those of RA or the more common“wear and tear”arthritis called osteoarthritis. Either diagnosis should be confirmed by someone who is an expert in arthritic diseases, usually a rheumatologist.

Here are six rheumatoid arthritis warning signs and how they differ from signs of osteoarthritis.

1. Usually with RA, one or more of your finger-knuckle joints will be swollen. The swelling is more likely to be in the middle or large knuckles of your hands — not the knuckles at the tips of your fingers next to your fingernails. It is often in joints on both hands. The swelling does not feel “bony,” but rather tender and slightly soft. With RA, you may also feel warmth and notice redness over the joint.

2. If at least one of your middle or large knuckles has been swollen and painful for more than six weeks, for no clear reason or explanation, it could be a sign of RA. Large joints such as your ankles, knees, shoulders, or elbows may be involved, but you must have swelling and pain in at least two joints to be diagnosed with rheumatoid arthritis.


On the other hand, swelling or pain in your small fingertip knuckles, at the base of your thumbs, and in your big toe joints will more often be due to osteoarthritis.

3. The balls of your feet are also targets for RA. Often, people with rheumatoid arthritis experience a feeling of“walking on golf balls” or swelling under the foot, especially first thing in the morning when you’re getting out of bed.

This pain will feel different from pain caused by a bunion. Pain from a bunion is usually at the base of the big toe, and feels worse when you wear tight shoes.

4. You just don’t feel well, and you may notice bumps on your elbows. With RA, you may have flu-like symptoms such as low-grade fevers and fatigue.

Occasionally, small tender bumps or nodules under the skin will develop with RA, often near the back of the elbow. These are called rheumatoid nodules.


5. Your joints are particularly stiff for more than an hour in the morning. With rheumatoid arthritis, you may find it difficult to completely make a fist. You may have unusually tender swelling on the top of your wrists. If your elbows are involved, it may be difficult for you to straighten them completely.

Usually, you won’t have swelling or pain in your hip joints early in the course of RA. Painful hip joints more often are due to osteoarthritis, and most people feel the pain in the front of the hip or in the groin region.

6. Certain blood tests may help determine whether you have RA. These are usually ordered by your health provider, but there are companies that allow you to order these tests yourself (Hint: Google search “order your own lab tests”).

Four important tests are usually ordered for an RA diagnosis. Two measure proteins in your blood called antibodies: Rf (rheumatoid factor) and CCP (anti-cyclic citrullinated peptide). The other two measure inflammation: ESR (erythrocyte sedimentation rate) and CRP (C-reactive protein). With RA, at least one Rf or CCP test must be positive and at least one CRP or ESR test must be abnormal.


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